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The usage of drugs for the treatment and prevention of deseases starts with their administration into the organism or application onto the body surface. The route of administration defines the speed of onset of effect, its intensity and duration. In certain cases the route of administration determines how the medications work.">The usage of drugs for the treatment and prevention of deseases starts with their administration into the organism or application onto the body surface. The route of administration defines the speed of onset of effect, its intensity and duration. In certain cases the route of administration determines how the medications work.The usage of drugs for the treatment and prevention of deseases starts with their administration into the organism or application onto the body surface. The route of administration defines the speed of onset of effect, its intensity and duration. In certain cases the route of administration determines how the medications work. usage of drugs for the treatment and prevention of deseases starts with their administration into the organism or application onto the body surface. The route of administration defines the speed of onset of effect, its intensity and duration. In certain cases the route of administration determines how the medications work.sage of drugs for the treatment and prevention of deseases starts with their administration into the organism or application onto the body surface. The route of administration defines the speed of onset of effect, its intensity and duration. In certain cases the route of administration determines how the medications work.ge of drugs for the treatment and prevention of deseases starts with their administration into the organism or application onto the body surface. The route of administration defines the speed of onset of effect, its intensity and duration. In certain cases the route of administration determines how the medications work.and prevention of deseases starts with their administration into the organism or application onto the body surface. The route of administration defines the speed of onset of effect, its intensity and duration. In certain cases the route of administration determines how the medications work.d prevention of deseases starts with their administration into the organism or application onto the body surface. The route of administration defines the speed of onset of effect, its intensity and duration. In certain cases the route of administration determines how the medications work.prevention of deseases starts with their administration into the organism or application onto the body surface. The route of administration defines the speed of onset of effect, its intensity and duration. In certain cases the route of administration determines how the medications work.evention of deseases starts with their administration into the organism or application onto the body surface. The route of administration defines the speed of onset of effect, its intensity and duration. In certain cases the route of administration determines how the medications work.ention of deseases starts with their administration into the organism or application onto the body surface. The route of administration defines the speed of onset of effect, its intensity and duration. In certain cases the route of administration determines how the medications work.tion of deseases starts with their administration into the organism or application onto the body surface. The route of administration defines the speed of onset of effect, its intensity and duration. In certain cases the route of administration determines how the medications work.of deseases starts with their administration into the organism or application onto the body surface. The route of administration defines the speed of onset of effect, its intensity and duration. In certain cases the route of administration determines how the medications work. deseases starts with their administration into the organism or application onto the body surface. The route of administration defines the speed of onset of effect, its intensity and duration. In certain cases the route of administration determines how the medications work.eseases starts with their administration into the organism or application onto the body surface. The route of administration defines the speed of onset of effect, its intensity and duration. In certain cases the route of administration determines how the medications work.cation onto the body surface. The route of administration defines the speed of onset of effect, its intensity and duration. In certain cases the route of administration determines how the medications work.tion onto the body surface. The route of administration defines the speed of onset of effect, its intensity and duration. In certain cases the route of administration determines how the medications work.on onto the body surface. The route of administration defines the speed of onset of effect, its intensity and duration. In certain cases the route of administration determines how the medications work.o the body surface. The route of administration defines the speed of onset of effect, its intensity and duration. In certain cases the route of administration determines how the medications work.the body surface. The route of administration defines the speed of onset of effect, its intensity and duration. In certain cases the route of administration determines how the medications work.e body surface. The route of administration defines the speed of onset of effect, its intensity and duration. In certain cases the route of administration determines how the medications work.he route of administration defines the speed of onset of effect, its intensity and duration. In certain cases the route of administration determines how the medications work. route of administration defines the speed of onset of effect, its intensity and duration. In certain cases the route of administration determines how the medications work.oute of administration defines the speed of onset of effect, its intensity and duration. In certain cases the route of administration determines how the medications work.">Existing administration routes are usually subdivided into enteral (via digestive tract) and parenteral (not entering into the digestive tract).pan class="">Existing administration routes are usually subdivided into enteral (via digestive tract) and parenteral (not entering into the digestive tract).n class="">Existing administration routes are usually subdivided into enteral (via digestive tract) and parenteral (not entering into the digestive tract).class="">Existing administration routes are usually subdivided into enteral (via digestive tract) and parenteral (not entering into the digestive tract).ass="">Existing administration routes are usually subdivided into enteral (via digestive tract) and parenteral (not entering into the digestive tract)."">Existing administration routes are usually subdivided into enteral (via digestive tract) and parenteral (not entering into the digestive tract).>Existing administration routes are usually subdivided into enteral (via digestive tract) and parenteral (not entering into the digestive tract).xisting administration routes are usually subdivided into enteral (via digestive tract) and parenteral (not entering into the digestive tract).ing administration routes are usually subdivided into enteral (via digestive tract) and parenteral (not entering into the digestive tract).g administration routes are usually subdivided into enteral (via digestive tract) and parenteral (not entering into the digestive tract).nistration routes are usually subdivided into enteral (via digestive tract) and parenteral (not entering into the digestive tract).stration routes are usually subdivided into enteral (via digestive tract) and parenteral (not entering into the digestive tract).ration routes are usually subdivided into enteral (via digestive tract) and parenteral (not entering into the digestive tract).re usually subdivided into enteral (via digestive tract) 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entering into the digestive tract).nd parenteral (not entering into the digestive tract). parenteral (not entering into the digestive tract).ssclass="">Enteral administration comprises oral, sublingual, transbuccal1, duodenal and rectal routes.ass="">Enteral administration comprises oral, sublingual, transbuccal1, duodenal and rectal routes.s="">Enteral administration comprises oral, sublingual, transbuccal1, duodenal and rectal routes.tal routes.l routes.routes.utes.es../span>n>lassss mg src="https://prior.studentlibrary.ru/cgi-bin/mb4x?usr_data=gd-image(doc,ISBN9785970438831-0005,pic_0014.jpg,-1,,00000000,)&hide_Cookie=yes" asis-dx="1062" asis-dy="1526" popup="POPUP-Xz17-pic_0014.jpg;911;1309" onClick="{{;;call_submit('frm_rds','rds','rds|rds','popup_image(doc,ISBN9785970438831-0005,POPUP-Xz17-pic_0014.jpg,911,1309)');}return false;}" style="padding:3 3 3 3px;border:1px dotted 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A number of drugs are taken transbuccally as polymer pastilles. Their active components are absorbed via the oral mucous membrane.lass="">1 From Latin bucca - cheek. A number of drugs are taken transbuccally as polymer pastilles. Their active components are absorbed via the oral mucous membrane.ss="">1 From Latin bucca - cheek. A number of drugs are taken transbuccally as polymer pastilles. Their active components are absorbed via the oral mucous membrane."">1 From Latin bucca - cheek. A number of drugs are taken transbuccally as polymer pastilles. Their active components are absorbed via the oral mucous membrane.>1 From Latin bucca - cheek. A number of drugs are taken transbuccally as polymer pastilles. Their active components are absorbed via the oral mucous membrane.span>1 From Latin bucca - cheek. A number of drugs are taken transbuccally as polymer pastilles. Their active components are absorbed via the oral mucous membrane.i>bucca - cheek. A number of drugs are taken transbuccally as polymer pastilles. Their active components are absorbed via the oral mucous membrane.bucca - cheek. A number of drugs are taken transbuccally as polymer pastilles. Their active components are absorbed via the oral mucous membrane.cca - cheek. A number of drugs are taken transbuccally as polymer pastilles. Their active components are absorbed via the oral mucous membrane.a - cheek. A number of drugs are taken transbuccally as polymer pastilles. Their active components are absorbed via the oral mucous membrane.- cheek. A number of drugs are taken transbuccally as polymer pastilles. Their active components are absorbed via the oral mucous membrane.i>- cheek. A number of drugs are taken transbuccally as polymer pastilles. Their active components are absorbed via the oral mucous membrane.heek. A number of drugs are taken transbuccally as polymer pastilles. Their active components are absorbed via the oral mucous membrane.ek. A number of drugs are taken transbuccally as polymer pastilles. Their active components are absorbed via the oral mucous membrane.. A number of drugs are taken transbuccally as polymer pastilles. Their active components are absorbed via the oral mucous membrane.heir active components are absorbed via the oral mucous membrane.ir active components are absorbed via the oral mucous membrane. active components are absorbed via the oral mucous membrane.e components are absorbed via the oral mucous membrane.components are absorbed via the oral mucous membrane.mponents are absorbed via the oral mucous membrane.rbed via the oral mucous membrane.ed via the oral mucous membrane. via the oral mucous membrane.pann classs="ter_footr_footlasss="ost common administration route is oral (by mouth; internally; per os). This is the most convenient and simple route of administration. Drugs do not have to be sterile to be administered this way. Absorption1 of a number of substances (for example, acetylsalicylic acid, barbiturates and other weak electrolytes possessing an acidic nature) occurs partially in the stomach2 (Fig. II.2). However, the majority of drugs are mainly absorbed in the small intestine. This is a favorable place for absorption due to the large absorbing surface of the intestinal mucous membrane (approximately 200 m2) and its intensive blood supply.t common administration route is oral (by mouth; internally; per os). This is the most convenient and simple route of administration. Drugs do not have to be sterile to be administered this way. Absorption1 of a number of substances (for example, acetylsalicylic acid, barbiturates and other weak electrolytes possessing an acidic nature) occurs partially in the stomach2 (Fig. II.2). However, the majority of drugs are mainly absorbed in the small intestine. This is a favorable place for absorption due to the large absorbing surface of the intestinal mucous membrane (approximately 200 m2) and its intensive blood supply.common administration route is oral (by mouth; internally; per os). This is the most convenient and simple route of administration. Drugs do not have to be sterile to be administered this way. Absorption1 of a number of substances (for example, acetylsalicylic acid, barbiturates and other weak electrolytes possessing an acidic nature) occurs partially in the stomach2 (Fig. II.2). However, the majority of drugs are mainly absorbed in the small intestine. This is a favorable place for absorption due to the large absorbing surface of the intestinal mucous membrane (approximately 200 m2) and its intensive blood supply.mmon administration route is oral (by mouth; internally; per os). This is the most convenient and simple route of administration. Drugs do not have to be sterile to be administered this way. Absorption1 of a number of substances (for example, acetylsalicylic acid, barbiturates and other weak electrolytes possessing an acidic nature) occurs partially in the stomach2 (Fig. II.2). However, the majority of drugs are mainly absorbed in the small intestine. This is a favorable place for absorption due to the large absorbing surface of the intestinal mucous membrane (approximately 200 m2) and its intensive blood supply.on administration route is oral (by mouth; internally; per os). This is the most convenient and simple route of administration. Drugs do not have to be sterile to be administered this way. Absorption1 of a number of substances (for example, acetylsalicylic acid, barbiturates and other weak electrolytes possessing an acidic nature) occurs partially in the stomach2 (Fig. II.2). However, the majority of drugs are mainly absorbed in the small intestine. This is a favorable place for absorption due to the large absorbing surface of the intestinal mucous membrane (approximately 200 m2) and its intensive blood supply. administration route is oral (by mouth; internally; per os). This is the most convenient and simple route of administration. Drugs do not have to be sterile to be administered this way. Absorption1 of a number of substances (for example, acetylsalicylic acid, barbiturates and other weak electrolytes possessing an acidic nature) occurs partially in the stomach2 (Fig. II.2). However, the majority of drugs are mainly absorbed in the small intestine. This is a favorable place for absorption due to the large absorbing surface of the intestinal mucous membrane (approximately 200 m2) and its intensive blood supply.nistration route is oral (by mouth; internally; per os). This is the most convenient and simple route of administration. Drugs do not have to be sterile to be administered this way. Absorption1 of a number of substances (for example, acetylsalicylic acid, barbiturates and other weak electrolytes possessing an acidic nature) occurs partially in the stomach2 (Fig. II.2). However, the majority of drugs are mainly absorbed in the small intestine. This is a favorable place for absorption due to the large absorbing surface of the intestinal mucous membrane (approximately 200 m2) and its intensive blood supply.stration route is oral (by mouth; internally; per os). This is the most convenient and simple route of administration. Drugs do not have to be sterile to be administered this way. Absorption1 of a number of substances (for example, acetylsalicylic acid, barbiturates and other weak electrolytes possessing an acidic nature) occurs partially in the stomach2 (Fig. II.2). However, the majority of drugs are mainly absorbed in the small intestine. This is a favorable place for absorption due to the large absorbing surface of the intestinal mucous membrane (approximately 200 m2) and its intensive blood supply.ration route is oral (by mouth; internally; per os). This is the most convenient and simple route of administration. Drugs do not have to be sterile to be administered this way. Absorption1 of a number of substances (for example, acetylsalicylic acid, barbiturates and other weak electrolytes possessing an acidic nature) occurs partially in the stomach2 (Fig. II.2). However, the majority of drugs are mainly absorbed in the small intestine. This is a favorable place for absorption due to the large absorbing surface of the intestinal mucous membrane (approximately 200 m2) and its intensive blood supply. the most convenient and simple route of administration. Drugs do not have to be sterile to be administered this way. Absorption1 of a number of substances (for example, acetylsalicylic acid, barbiturates and other weak electrolytes possessing an acidic nature) occurs partially in the stomach2 (Fig. II.2). However, the majority of drugs are mainly absorbed in the small intestine. This is a favorable place for absorption due to the large absorbing surface of the intestinal mucous membrane (approximately 200 m2) and its intensive blood supply.he most convenient and simple route of administration. Drugs do not have to be sterile to be administered this way. Absorption1 of a number of substances (for example, acetylsalicylic acid, barbiturates and other weak electrolytes possessing an acidic nature) occurs partially in the stomach2 (Fig. II.2). However, the majority of drugs are mainly absorbed in the small intestine. This is a favorable place for absorption due to the large absorbing surface of the intestinal mucous membrane (approximately 200 m2) and its intensive blood supply. most convenient and simple route of administration. Drugs do not have to be sterile to be administered this way. Absorption1 of a number of substances (for example, acetylsalicylic acid, barbiturates and other weak electrolytes possessing an acidic nature) occurs partially in the stomach2 (Fig. II.2). However, the majority of drugs are mainly absorbed in the small intestine. This is a favorable place for absorption due to the large absorbing surface of the intestinal mucous membrane (approximately 200 m2) and its intensive blood supply.convenient and simple route of administration. Drugs do not have to be sterile to be administered this way. Absorption1 of a number of substances (for example, acetylsalicylic acid, barbiturates and other weak electrolytes possessing an acidic nature) occurs partially in the stomach2 (Fig. II.2). However, the majority of drugs are mainly absorbed in the small intestine. This is a favorable place for absorption due to the large absorbing surface of the intestinal mucous membrane (approximately 200 m2) and its intensive blood supply.nvenient and simple route of administration. Drugs do not have to be sterile to be administered this way. Absorption1 of a number of substances (for example, acetylsalicylic acid, barbiturates and other weak electrolytes possessing an acidic nature) occurs partially in the stomach2 (Fig. II.2). However, the majority of drugs are mainly absorbed in the small intestine. This is a favorable place for absorption due to the large absorbing surface of the intestinal mucous membrane (approximately 200 m2) and its intensive blood supply.enient and simple route of administration. Drugs do not have to be sterile to be administered this way. Absorption1 of a number of substances (for example, acetylsalicylic acid, barbiturates and other weak electrolytes possessing an acidic nature) occurs partially in the stomach2 (Fig. II.2). However, the majority of drugs are mainly absorbed in the small intestine. This is a favorable place for absorption due to the large absorbing surface of the intestinal mucous membrane (approximately 200 m2) and its intensive blood supply. route of administration. Drugs do not have to be sterile to be administered this way. Absorption1 of a number of substances (for example, acetylsalicylic acid, barbiturates and other weak electrolytes possessing an acidic nature) occurs partially in the stomach2 (Fig. II.2). However, the majority of drugs are mainly absorbed in the small intestine. This is a favorable place for absorption due to the large absorbing surface of the intestinal mucous membrane (approximately 200 m2) and its intensive blood supply.oute of administration. Drugs do not have to be sterile to be administered this way. Absorption1 of a number of substances (for example, acetylsalicylic acid, barbiturates and other weak electrolytes possessing an acidic nature) occurs partially in the stomach2 (Fig. II.2). However, the majority of drugs are mainly absorbed in the small intestine. This is a favorable place for absorption due to the large absorbing surface of the intestinal mucous membrane (approximately 200 m2) and its intensive blood supply.te of administration. Drugs do not have to be sterile to be administered this way. Absorption1 of a number of substances (for example, acetylsalicylic acid, barbiturates and other weak electrolytes possessing an acidic nature) occurs partially in the stomach2 (Fig. II.2). However, the majority of drugs are mainly absorbed in the small intestine. This is a favorable place for absorption due to the large absorbing surface of the intestinal mucous membrane (approximately 200 m2) and its intensive blood supply.nistered this way. Absorption1 of a number of substances (for example, acetylsalicylic acid, barbiturates and other weak electrolytes possessing an acidic nature) occurs partially in the stomach2 (Fig. II.2). However, the majority of drugs are mainly absorbed in the small intestine. This is a favorable place for absorption due to the large absorbing surface of the intestinal mucous membrane (approximately 200 m2) and its intensive blood supply.stered this way. Absorption1 of a number of substances (for example, acetylsalicylic acid, barbiturates and other weak electrolytes possessing an acidic nature) occurs partially in the stomach2 (Fig. II.2). However, the majority of drugs are mainly absorbed in the small intestine. This is a favorable place for absorption due to the large absorbing surface of the intestinal mucous membrane (approximately 200 m2) and its intensive blood supply.ered this way. Absorption1 of a number of substances (for example, acetylsalicylic acid, barbiturates and other weak electrolytes possessing an acidic nature) occurs partially in the stomach2 (Fig. II.2). However, the majority of drugs are mainly absorbed in the small intestine. This is a favorable place for absorption due to the large absorbing surface of the intestinal mucous membrane (approximately 200 m2) and its intensive blood supply.ed this way. Absorption1 of a number of substances (for example, acetylsalicylic acid, barbiturates and other weak electrolytes possessing an acidic nature) occurs partially in the stomach2 (Fig. II.2). However, the majority of drugs are mainly absorbed in the small intestine. This is a favorable place for absorption due to the large absorbing surface of the intestinal mucous membrane (approximately 200 m2) and its intensive blood supply. this way. Absorption1 of a number of substances (for example, acetylsalicylic acid, barbiturates and other weak electrolytes possessing an acidic nature) occurs partially in the stomach2 (Fig. II.2). However, the majority of drugs are mainly absorbed in the small intestine. This is a favorable place for absorption due to the large absorbing surface of the intestinal mucous membrane (approximately 200 m2) and its intensive blood supply.his way. Absorption1 of a number of substances (for example, acetylsalicylic acid, barbiturates and other weak electrolytes possessing an acidic nature) occurs partially in the stomach2 (Fig. II.2). However, the majority of drugs are mainly absorbed in the small intestine. This is a favorable place for absorption due to the large absorbing surface of the intestinal mucous membrane (approximately 200 m2) and its intensive blood supply.s way. Absorption1 of a number of substances (for example, acetylsalicylic acid, barbiturates and other weak electrolytes possessing an acidic nature) occurs partially in the stomach2 (Fig. II.2). However, the majority of drugs are mainly absorbed in the small intestine. This is a favorable place for absorption due to the large absorbing surface of the intestinal mucous membrane (approximately 200 m2) and its intensive blood supply.y. Absorption1 of a number of substances (for example, acetylsalicylic acid, barbiturates and other weak electrolytes possessing an acidic nature) occurs partially in the stomach2 (Fig. II.2). However, the majority of drugs are mainly absorbed in the small intestine. This is a favorable place for absorption due to the large absorbing surface of the intestinal mucous membrane (approximately 200 m2) and its intensive blood supply. Absorption1 of a number of substances (for example, acetylsalicylic acid, barbiturates and other weak electrolytes possessing an acidic nature) occurs partially in the stomach2 (Fig. II.2). However, the majority of drugs are mainly absorbed in the small intestine. This is a favorable place for absorption due to the large absorbing surface of the intestinal mucous membrane (approximately 200 m2) and its intensive blood supply.bsorption1 of a number of substances (for example, acetylsalicylic acid, barbiturates and other weak electrolytes possessing an acidic nature) occurs partially in the stomach2 (Fig. II.2). However, the majority of drugs are mainly absorbed in the small intestine. This is a favorable place for absorption due to the large absorbing surface of the intestinal mucous membrane (approximately 200 m2) and its intensive blood supply.ption1 of a number of substances (for example, acetylsalicylic acid, barbiturates and other weak electrolytes possessing an acidic nature) occurs partially in the stomach2 (Fig. II.2). However, the majority of drugs are mainly absorbed in the small intestine. 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However, the majority of drugs are mainly absorbed in the small intestine. This is a favorable place for absorption due to the large absorbing surface of the intestinal mucous membrane (approximately 200 m2) and its intensive blood supply. partially in the stomach2 (Fig. II.2). However, the majority of drugs are mainly absorbed in the small intestine. This is a favorable place for absorption due to the large absorbing surface of the intestinal mucous membrane (approximately 200 m2) and its intensive blood supply.artially in the stomach2 (Fig. II.2). However, the majority of drugs are mainly absorbed in the small intestine. This is a favorable place for absorption due to the large absorbing surface of the intestinal mucous membrane (approximately 200 m2) and its intensive blood supply.ly in the stomach2 (Fig. II.2). However, the majority of drugs are mainly absorbed in the small intestine. 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< class="txtlass="">Fig. II.2. Importance of the pH of the medium for the absorption of substances from the stomach.ss="">Fig. II.2. Importance of the pH of the medium for the absorption of substances from the stomach.="">Fig. II.2. Importance of the pH of the medium for the absorption of substances from the stomach.>Fig. II.2. Importance of the pH of the medium for the absorption of substances from the stomach.b>Fig. II.2. Importance of the pH of the medium for the absorption of substances from the stomach.Fig. II.2. Importance of the pH of the medium for the absorption of substances from the stomach.he pH of the medium for the absorption of substances from the stomach. pH of the medium for the absorption of substances from the stomach.H of the medium for the absorption of substances from the stomach.of the medium for the absorption of substances from the stomach. the medium for the absorption of substances from the stomach.he medium for the absorption of substances from the stomach.dium for the absorption of substances from the stomach.um for the absorption of substances from the stomach. for the absorption of substances from the stomach.

There are several known absorption mechanisms (Fig. II.3).ss="">There are several known absorption mechanisms (Fig. II.3).="">There are several known absorption mechanisms (Fig. II.3)."">Passive diffusion occurs via the cellular membrane. It is defined by the concentration gradient of the compound. Lipophilic substances (mainly nonpolar) are easily absorbed via this route. The higher the lipophility of substances, the easier they penetrate through the cell membrane.>Passive diffusion occurs via the cellular membrane. It is defined by the concentration gradient of the compound. Lipophilic substances (mainly nonpolar) are easily absorbed via this route. The higher the lipophility of substances, the easier they penetrate through the cell membrane.i>Passive diffusion occurs via the cellular membrane. It is defined by the concentration gradient of the compound. Lipophilic substances (mainly nonpolar) are easily absorbed via this route. The higher the lipophility of substances, the easier they penetrate through the cell membrane.Passive diffusion occurs via the cellular membrane. It is defined by the concentration gradient of the compound. Lipophilic substances (mainly nonpolar) are easily absorbed via this route. The higher the lipophility of substances, the easier they penetrate through the cell membrane.ssive diffusion occurs via the cellular membrane. It is defined by the concentration gradient of the compound. Lipophilic substances (mainly nonpolar) are easily absorbed via this route. The higher the lipophility of substances, the easier they penetrate through the cell membrane.ive diffusion occurs via the cellular membrane. It is defined by the concentration gradient of the compound. Lipophilic substances (mainly nonpolar) are easily absorbed via this route. The higher the lipophility of substances, the easier they penetrate through the cell membrane.e diffusion occurs via the cellular membrane. It is defined by the concentration gradient of the compound. Lipophilic substances (mainly nonpolar) are easily absorbed via this route. The higher the lipophility of substances, the easier they penetrate through the cell membrane.ffusion occurs via the cellular membrane. It is defined by the concentration gradient of the compound. Lipophilic substances (mainly nonpolar) are easily absorbed via this route. The higher the lipophility of substances, the easier they penetrate through the cell membrane.usion occurs via the cellular membrane. It is defined by the concentration gradient of the compound. Lipophilic substances (mainly nonpolar) are easily absorbed via this route. The higher the lipophility of substances, the easier they penetrate through the cell membrane.ion occurs via the cellular membrane. It is defined by the concentration gradient of the compound. Lipophilic substances (mainly nonpolar) are easily absorbed via this route. The higher the lipophility of substances, the easier they penetrate through the cell membrane.occurs via the cellular membrane. It is defined by the concentration gradient of the compound. Lipophilic substances (mainly nonpolar) are easily absorbed via this route. The higher the lipophility of substances, the easier they penetrate through the cell membrane.i>occurs via the cellular membrane. It is defined by the concentration gradient of the compound. Lipophilic substances (mainly nonpolar) are easily absorbed via this route. The higher the lipophility of substances, the easier they penetrate through the cell membrane.rs via the cellular membrane. It is defined by the concentration gradient of the compound. Lipophilic substances (mainly nonpolar) are easily absorbed via this route. The higher the lipophility of substances, the easier they penetrate through the cell membrane. via the cellular membrane. It is defined by the concentration gradient of the compound. Lipophilic substances (mainly nonpolar) are easily absorbed via this route. The higher the lipophility of substances, the easier they penetrate through the cell membrane.ia the cellular membrane. It is defined by the concentration gradient of the compound. Lipophilic substances (mainly nonpolar) are easily absorbed via this route. The higher the lipophility of substances, the easier they penetrate through the cell membrane. membrane. It is defined by the concentration gradient of the compound. Lipophilic substances (mainly nonpolar) are easily absorbed via this route. The higher the lipophility of substances, the easier they penetrate through the cell membrane.embrane. It is defined by the concentration gradient of the compound. Lipophilic substances (mainly nonpolar) are easily absorbed via this route. The higher the lipophility of substances, the easier they penetrate through the cell membrane.brane. It is defined by the concentration gradient of the compound. Lipophilic substances (mainly nonpolar) are easily absorbed via this route. The higher the lipophility of substances, the easier they penetrate through the cell membrane.ne. It is defined by the concentration gradient of the compound. Lipophilic substances (mainly nonpolar) are easily absorbed via this route. The higher the lipophility of substances, the easier they penetrate through the cell membrane.. It is defined by the concentration gradient of the compound. Lipophilic substances (mainly nonpolar) are easily absorbed via this route. The higher the lipophility of substances, the easier they penetrate through the cell membrane.It is defined by the concentration gradient of the compound. Lipophilic substances (mainly nonpolar) are easily absorbed via this route. The higher the lipophility of substances, the easier they penetrate through the cell membrane.tion gradient of the compound. Lipophilic substances (mainly nonpolar) are easily absorbed via this route. The higher the lipophility of substances, the easier they penetrate through the cell membrane.on gradient of the compound. Lipophilic substances (mainly nonpolar) are easily absorbed via this route. The higher the lipophility of substances, the easier they penetrate through the cell membrane. gradient of the compound. Lipophilic substances (mainly nonpolar) are easily absorbed via this route. The higher the lipophility of substances, the easier they penetrate through the cell membrane.radient of the compound. Lipophilic substances (mainly nonpolar) are easily absorbed via this route. The higher the lipophility of substances, the easier they penetrate through the cell membrane.dient of the compound. Lipophilic substances (mainly nonpolar) are easily absorbed via this route. The higher the lipophility of substances, the easier they penetrate through the cell membrane.ent of the compound. Lipophilic substances (mainly nonpolar) are easily absorbed via this route. 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