Глава 30. ГЛАЗНЫЕ ЛЕКАРСТВЕННЫЕ ФОРМЫ

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Глава 20. СУСПЕНЗИИ +

Глава 21. ЭМУЛЬСИИ +

Глава 22. СБОРЫ (SPECIES)+

Глава 23. НАСТОИ И ОТВАРЫ (INFUSA ET DECOCTA)+

Глава 24. ФАРМАЦЕВТИЧЕСКАЯ НЕСОВМЕСТИМОСТЬ ЖИДКИХ ЛЕКАРСТВЕННЫХ ФОРМ И СПОСОБЫ ЕЕ ПРЕДОТВРАЩЕНИЯ +

Глава 25. ИНЪЕКЦИОННЫЕ ЛЕКАРСТВЕННЫЕ ФОРМЫ +

Глава 26. ПЛАЗМОЗАМЕЩАЮЩИЕ РАСТВОРЫ (SOLUTIONES PLASMOSUBSTITUENTES)+

Глава 27. МАЗИ (UNGUENTA)+

Глава 28. ЛИНИМЕНТЫ +

Глава 29. СУППОЗИТОРИИ +

Глава 30. ГЛАЗНЫЕ ЛЕКАРСТВЕННЫЕ ФОРМЫ -

30.1. Требования государственной фармакопеи

30.2. Технология изготовления глазных капель

30.2.1. Обеспечение стерильности

30.2.2. Обеспечение отсутствия механических включений

30.2.3. Обеспечение точности дозирования лекарственных средств

30.2.4. Обеспечение комфортности

30.2.5. Регулирование рН

30.2.6. Обеспечение химической стабильности

30.2.7. Обеспечение пролонгирования действия

30.3. Тара и упаковка для фасовки офтальмологических растворов

30.4. Оборудование для изготовления глазных капель

30.5. Технологическая схема изготовления глазных капель и растворов

30.6. Примеры изготовления глазных капель

30.7. Глазные растворы

30.8. Глазные мази

30.8.1. Основы для глазных мазей

30.8.2. Технология изготовления глазных мазей

Приложение

Глава 31. ЛЕКАРСТВЕННЫЕ ФОРМЫ ДЛЯ ДЕТЕЙ +

Глава 32. ЛЕКАРСТВЕННЫЕ ФОРМЫ С АНТИБИОТИКАМИ +

Question 2. Role, value, and tasks of sanitary microbiology. Indicator microorganisms

Question 3. Microflora of water. Methods of microbiological research of water. Indicator microorganisms of water

Question 4. Microflora of soil. Methods of microbiological research of soil. Indicator microorganisms of soil

Question 5. Microflora of air. Methods of microbiological research of air. Indicator microorganisms of air

Question 6. The normal microflora of the human body and its significance

Question 7. Factors that change the normal microflora of the organism. Dysbacteriosis, ways of its treatment

Test for unit 1

Unit 2. Immunology

Lecture 1. Immunology as a science. Introduction in immunology

Question 1. Immunology, its definition

Question 2. The history of immunology, the main periods in the development of immunology

Question 3. Sections of modern immunology. The concept of immunity. Classification of immunity

Question 4. Structure of the immune system. The primary (central) organs of the immune system

Question 5. The secondary organs of the immune system

Question 6. The role of blood cells in immunity

Question 7. The primary cell populations of the immune system

Question 8. Scheme of the immune response

Lecture 2. Innate immunity. Factors and mechanisms of the innate immunity. The concept of a non-specific (innate) immunity. The main barriers of nonspecific immunity

Question 1. The concept of a non-specific (innate) immunity. The main barriers of nonspecific immunity

Question 2. The innate immune factors — skin and mucous membranes

Question 3. Lysozyme — chemical composition and function. Normal microflora in human immunity

Question 4. Complement — chemical composition and functions

Question 5. The activation of the complement system

Question 6. Phagocytosis, mononuclear phagocyte system

Question 7. The functions of phagocytes. Opsonins

Question 8. Phagocytosis mechanism stage. «Oxygen explosion». Complete and incomplete phagocytosis

Question 9. Cytokines — definition, properties. The therapeutic use of cytokines

Question 10. Classification of cytokines

Question 11. Cytokines: interleukins, interferons

Question 12. Cytokines: tumour necrosis factor, colony-stimulating factors, transforming growth factor-β

Question 13. Protective serum proteins

Lecture 3. Antigens. Antibodies

Question 1. Antigens: definition, chemical composition

Question 2. The structure of the antigen

Question 3. Properties of antigens: antigenicity, immunogenicity, specificity, foreignness

Question 4. Classification antigens on its origin, the degree of immunogenicity

Question 5. Classification of antigens by the immune response. Haptens. Adjuvants

Question 6. The antigens of the human body

Question 7. The antigens of bacteria, viruses. autoantigens

Question 8. Antibodies: definition, structure

Question 9. Immunoglobulin classes. serum immunoglobulins

Question 10. The properties of antibodies

Question 11. Phases of antibody production

Question 12. Protective functions of antibodies

Lecture 4. Hypersensitivity. Immunological memory. Immunological tolerance

Question 1. Hypersensitivity, its definition. The definition of allergy. Stages of an allergic reaction

Question 2. Classification of allergies

Question 3. Type I of immediate-type hypersensitivity: anaphylaxis (mechanism of development, manifestations of anaphylaxis, its treatment). Anaphylactic shock

Question 4. Type II of immediate hypersensitivity (cytotoxic): mechanisms of development, clinical manifestations

Question 5. III type of immediate hypersensitivity reactions (immune complex), mechanisms of development, clinical manifestations

Question 6. Delayed type of hypersensitivity: mechanism of development, manifestations of contact allergy

Question 7. Classification of allergens. infectious allergy

Question 8. Drug allergies: the immune response to the drug (haptens), clinical manifestations of drug allergy

Question 9. Laboratory diagnosis of allergies

Question 10. Immunological memory: concept, mechanisms

Question 11. Immunological tolerance: concept, causes, mechanisms

Lecture 5. Pathology of the immune system

Question 1. The definition of immunodeficiency, the classification of immunodeficiencies

Question 2. Primary immunodeficiencies: characteristics, classification

Question 3. Primary immunodeficiencies: T-cell deficiencies

Question 4. Primary immunodeficiencies: combined B-cell and T-cell deficiencies

Question 5. Primary immunodeficiencies: disorders of the complement system (complement deficiencies)

Question 6. Primary immunodeficiencies: phagocyte deficiencies

Question 7. Secondary (acquired) immunodeficiency: causes, characteristics, classification

Question 8. Clinical manifestations of immunodeficiency states

Lecture 6. Evaluation of the immune status

Question 1. Laboratory diagnosis of immunodeficiencies in children and adults: methods, assessment criteria, interpretation

Question 2. Methods of assessing the immune status

Question 3. The levels of evaluation of the immune status

Question 4. First-stage tests (tentative)

Question 5. The second-stage tests (analytical) in the evaluation of the immune status

Question 6. General rules of immunogram evaluation

Lecture 7. Serological tests: agglutination, precipitation test, complement fixation test, tests using labeled antibodies and antigens (ELISA, IFT, RIA)

Question 1. Serological tests: definition, classification and practical use

Question 2. Agglutination test: definition, mechanism, classification and practical use

Question 3. Direct agglutination tests: mechanism and practical use

Question 4. Indirect (passive) agglutination tests: mechanism and practical use

Question 5. Precipitation reaction: identification, mechanism, types, practical use

Question 6. Complement fixation test (CFT): the purpose of its carrying out, components, mechanisms

Question 7. Labelling methods for detection antigen-antibody binding

Question 8. Immunofluorescent test

Question 9. Enzyme-linked immunosorbent assay

Question 10. Radioimmunoassay (RIA)

Question 11. Western blotting (immunoblotting)

Lecture 8. Specific prevention and treatment of infectious diseases. Therapeutic, prophylactic, and diagnostic immunological preparations

Question 1. Immunoprophylaxis, immunotherapy: definitions

Question 2. The history of immunisation

Question 3. Vaccines — classification, characteristics

Question 4. Complications after vaccines, contraindications to immunisation. scheme of vaccine use

Question 5. The immunological antibody-based drugs. Classification. Characteristic (passive immunisation)

Question 6. Rules of vaccines and serums injection. Routes of vaccine injection

Lecture 9. Antiviral and antibacterial immunity. immunity in transplantation, cancer and immunity in mycoses. Immunity and age

Question 1. Features of local immunity — skin and mucous membranes

Question 2. Antibacterial and antitoxic immunity. Factors of antibacterial immunity

Question 3. Antiviral immunity

Question 4. Antifungal immunity

Question 5. Immunity in protozoa and parasitic infections

Question 6. Immunity in transplantation

Question 7. Antitumor immunity

Question 8. Immunity in pregnancy

Question 9. Age features of immunity

Test for unit 2

Раrt 2. Special Microbiology, Mycology and Virology +

Key answers for Test

List of literature