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Clinical genetics
Оборот титула
Оглавление
List of symbols and abbreviations
Introduction
Chapter 1. Introduction to clinical genetics
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Chapter 2. Heredity and pathology
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Chapter 3. Semiotics and clinical diagnostics of inherited diseases
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Chapter 4. Genetic diseases
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Chapter 5. Chromosomal disorders
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Chapter 6. Diseases with hereditary predisposition
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Chapter 7. Ecological genetics
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Chapter 8. Pharmacogenetics
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Chapter 9. Laboratory diagnostic methods
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Chapter 10. Guidelines for treatment of hereditary diseases
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General issues
Symptomatic treatment
Pathogenetic treatment
Correction of metabolism at the substrate level
Correction of metabolism at the gene product level
Correction of metabolism at the enzyme level
Modification of enzymatic activity
Enzyme compensation therapy
Surgical treatment
Etiotropic treatment: cell and gene therapy
Introduction
Cell therapy
Gene therapy
Transgenic cell therapy
Therapeutic modulation of gene expression
Risks of cellular and gene therapy
Conclusion
Keywords and concepts
Recommended bibliography
Chapter 11. Prevention of hereditary pathology
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Chapter 12. Ethical issues in medical genetics
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Test questions
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Appendix
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12
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16
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3
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23
Chapter 10. Guidelines for treatment of hereditary diseases
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Clinical genetics
Оглавление
List of symbols and abbreviations
Introduction
Chapter 1. Introduction to clinical genetics
+
Chapter 2. Heredity and pathology
+
Chapter 3. Semiotics and clinical diagnostics of inherited diseases
+
Chapter 4. Genetic diseases
+
Chapter 5. Chromosomal disorders
+
Chapter 6. Diseases with hereditary predisposition
+
Chapter 7. Ecological genetics
+
Chapter 8. Pharmacogenetics
+
Chapter 9. Laboratory diagnostic methods
+
Chapter 10. Guidelines for treatment of hereditary diseases
-
General issues
Symptomatic treatment
Pathogenetic treatment
Correction of metabolism at the substrate level
Correction of metabolism at the gene product level
Correction of metabolism at the enzyme level
Modification of enzymatic activity
Enzyme compensation therapy
Surgical treatment
Etiotropic treatment: cell and gene therapy
Introduction
Cell therapy
Gene therapy
Transgenic cell therapy
Therapeutic modulation of gene expression
Risks of cellular and gene therapy
Conclusion
Keywords and concepts
Recommended bibliography
Chapter 11. Prevention of hereditary pathology
+
Chapter 12. Ethical issues in medical genetics
+
Test questions
+
Appendix
+
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